- 10th MENACTRIMS Congress

ParadigMS Symposium Al Baraha 1 • December 4 • 13:30–15:00

Unfolding the Subject Matter:
Early intervention in Multiple Sclerosis (MS) has proven essential for optimizing long-term outcomes, as neurodegeneration often precedes overt clinical symptoms. Detecting subtle signs of progression through advanced imaging, biomarkers, and functional assessments allows for timely therapeutic adjustments that may preserve neurological function. As treatment options expand, integrating early detection strategies into routine practice becomes key to personalizing care and improving quality of life for people living with MS.

Key Takeaways
• Gain insights into the role of microglia in MS and how BTKi therapies may transform treatment.
• Understand prognostic factors that guide therapy selection in treatment-naïve patients.
• Learn to detect and monitor progression in MS using the latest clinical and imaging tools.
• Participate in a Q&A and expert panel to discuss practical strategies and future directions in MS management.
Venue
Al Baraha 1, Intercontinental Hotel – Festival City
Dubai, United Arab Emirates

Program

ParadigMS Session Table

Practical Strategies for Early Treatment and Detecting Progression in MS Chairs: B. Yamout (AE) & C. Oreja-Guevara (ES)
14:00–14:05	Welcome	B. Yamout (AE) & C. Oreja-Guevara (ES)
14:05–14:20	The Role of Microglia in Multiple Sclerosis: Implications for Treatment with Bruton’s Tyrosine Kinase Inhibitors	H.P. Hartung (DE)
14:20–14:35	Prognostic Factors for Evaluation of MS Therapy in Treatment Naive Patients	Magd Zakaria (EG)
14:35–14:50	How to Detect Progression in Multiple Sclerosis	C. Oreja-Guevara (ES)
14:50–15:00	Q&A and Panel Discussion	All faculty, facilitated by B. Yamout (AE)

Faculty

Prof. Bassem I. Yamout

Neurology Institute Director

Harley Street Medical Centre

Abu Dhabi, United Arab Emirates

Prof. Hans-Peter Hartung

Professor and Honorary Professor

Heinrich Heine Universität & University of Sydney

Düsseldorf, Germany

Prof. Magd Zakaria

Professor of Neurology

Ain Shams University

Cairo, Egypt

Prof. Celia Oreja-Guevara

Vice Chair of Neurology

University Hospital San Carlos

Madrid, Spain

Target Audience

Specialists
Neurologists

Practitioners
Researchers in the field of MS

Registration

Registration is complimentary and can be arranged via the online registration module upon registering for the congress pass.

What are the key takeaways from this Symposium?

By attending this symposium you will:

Discover the pivotal role of microglia in multiple sclerosis (MS) and how their interaction with the immune system shapes disease activity and progression. Learn how Bruton’s Tyrosine Kinase inhibitors (BTKi) are emerging as a promising treatment approach, offering new possibilities for personalized MS care. Presented by H.P. Hartung (Germany)
Understand key prognostic factors for evaluating MS therapy in treatment-naïve patients. Explore the latest insights on biomarkers, imaging, and early clinical indicators that can help optimize treatment selection and predict long-term outcomes. Presented by Magd Zakaria (Egypt)
Learn how to detect progression in MS through subtle clinical and radiological signs. Gain practical knowledge on using advanced tools to monitor disease activity, disability, and cognitive function over time. Presented by C. Oreja-Guevara (Spain)
Join an engaging Q&A and panel discussion with leading experts, where you can exchange perspectives, ask questions, and translate the latest evidence into real-world practice. Facilitated by B. Yamout (United Arab Emirates)